# Model Library

# Accessing the Model Library

Finch Studio comes with a model library with over 100 starting models to choose from. To access the model library, click the + icon next to the Models label on the left panel.

# Structural Model

When creating a model from the library, the first step will be to choose the structural model. You may browse the model library to find the model you wish to use, or you can apply filters based on the features you wish your model to have. The code for the model will be shown to the right of the model you have selected.

Note, you may notice the $INPUT, $DATA, and $TABLE blocks have already been filled in based on your data mapping. This makes the model control stream ready-to-run once you choose your model, although you also have the option to make further modifications before running the model.

# Parameter Model

The next step to create a model from the library is to specify which model parameters should have IIV included on them. Navigate to the Parameter Models tab. Click on the grid of checkboxes resembling the covariance matrix to add or remove IIV/correlations on and between parameters. Notice how the code is update to reflect the IIV matrix you have selected.

# Residual Error Model

Finally choose the residual error model you wish to implement. Built-in options include Additive, Proportional, Additive + Proportion, and Log-Normal.

# Overview of Available Model Components

# Administration

  • Intravenous (IV)
  • Extravascular (EV)

# Delay

  • None
  • Lag-time
  • Transit-approximation

# Absorption

  • Zero-order
  • First-order

# Distribution

  • 1-cmt
  • 2-cmt
  • 3-cmt

# Elimination

  • Linear
  • Michaelis-Mentin (MM)

# Advan/Trans

  • Built in NONMEM ADVANS (1, 2, 3, 4, 10, 11, 12)
  • General linear model (5)
  • Differential equations, LSODA (13)